How to apply suppositories Neo-Penotran


Infectious diseases of the reproductive system can hardly be considered a rarity in modern gynecological practice. Such diseases require appropriate treatment, since otherwise the appearance of various complications is not excluded. Quite popular today is the drug "Neo-Penotran" (candles). Reviews of doctors and patients indicate that this drug really does its job, quickly and effectively eliminating the infection and its main symptoms.

However, patients are often interested in additional information about this drug. What is its composition? What properties does it have? How to use candles? Is it possible the appearance of side effects during therapy? Answers to these questions will be interesting to many readers.

The composition and release form of the drug

According to surveys of patients and doctors, this drug is quite in demand. And it is quite natural that for many additional information about the drug is quite important.

The medicine is produced in the form of vaginal candles No. 7. Suppositories are placed in blister packs of seven pieces each. The main active ingredient of the drug is metronidazole - a substance with antimicrobial properties. In addition, miconazole nitrate is also present in the formulation. Witepsol in the amount of 1.9 g is used as the basis for the manufacture of suppositories.

Depending on the number of active substances, it is customary to distinguish the following types of drugs:

  • Candles "Neo-Penotran" contain 500 mg of metronidazole and 100 mg of miconazole nitrate.
  • Candles "Neo-Penotran Forte" have a large dose of active substances, namely, 750 mg of metronidazole and 200 mg of miconazole nitrate.
  • There are also vaginal suppositories “Neo-Penotran Forte-L”, which also contain metronidazole and miconazole nitrate in quantities of 750 and 200 mg, respectively. In addition, the drug includes lidocaine (100 mg).

What pharmacological properties of the drug?

This tool is a combination drug with pronounced antiparasitic and antimicrobial properties. In modern medicine it is widely used to treat protozoal and fungal infections. Some bacteria are also sensitive to active substances.

Once in the human body, the active components quickly suppress the vital processes of the pathogenic microflora. Metronidazole blocks the synthesis of nucleic acids, which prevents the further multiplication of microorganisms. Miconazole has a detrimental effect on fungal microorganisms, since it destroys their cell walls. By the way, cryptococci, candida and aspergillus are the most sensitive to this substance.

Basic indications for use

In which cases, patients are prescribed the drug "Neo-Penotran"? Vaginal suppositories are used to treat the following diseases:

  • vaginal candidiasis caused by increased reproduction of fungal microorganisms,
  • Trichomonas vulvovaginitis,
  • mixed vaginal infections (diseases triggered by several pathogenic microorganisms at once),
  • bacterial vaginosis.

Suppositories are used for topical treatment. Most often this is enough for a full and quick recovery. But in more severe cases, the doctor may also prescribe oral medications.

How to apply?

In no case should not use this drug alone. After all, you first need a thorough diagnosis, which is possible only in a medical institution. After the diagnosis, the doctor will select the appropriate form of the drug for you. For example, in more severe cases, Neo-Penotral Forte candles are used.

The vaginal suppository must be inserted deep into the vagina. For this purpose, special disposable fingertips are used, which are sold with the preparation. The procedure is preferably carried out in the evening, just before bedtime - this will allow the suppository to completely dissolve and wilt into the mucous tissues.

How long do I need to use candles "Neo-Penotran"? The instruction states that the course of treatment lasts no more than seven days. Only in the most severe cases (for example, in the presence of recurrent inflammations or resistant infections) can the doctor extend the course of treatment for another week and increase the daily dose to two suppositories.

Can I use the drug during pregnancy and lactation?

As already mentioned, this medicine is not used during the first 15 weeks of pregnancy, since during this period the main organs are laid down. In the future, suppositories are allowed to apply, but only after a thorough diagnosis and under the supervision of the attending physician.

The active components of the drug quickly penetrate into breast milk, so the lactation period is a contraindication to therapy. If the use of suppositories is still necessary, then at the time of treatment you need to stop breastfeeding.

Is it possible to use medicine during menstruation?

Many patients are also interested in the question of whether to use candles "Neo-Penotran" during menstruation. In fact, menstruation is not a contraindication to the use of the drug. Nevertheless, some gynecologists still recommend to wait for the end of the discharge.

On the other hand, if during the period of treatment the period began, then in no case should you interrupt the course. But you need to understand that you can not use vaginal tampons - they need to be replaced with sanitary pads.

Are there any contraindications?

Of course, many patients are interested in questions about whether the drug "Neo-Penotran" (candles) is contraindicated. Reviews confirm that the drug is usually well tolerated, but, unfortunately, not all categories of women can use it.

In particular, various disorders of the liver, as well as disorders of the functioning of the nervous system can be attributed to contraindications. The drug is not prescribed to virgins, girls under 15 years of age, as well as patients with hypersensitivity to any of the components of this tool. In addition, the list of contraindications should include epilepsy, convulsive states, bleeding disorders, as well as the first trimester of pregnancy.

Possible side effects

In fact, the body tolerates the drug “Neo-Penotran” (candles) quite well. Reviews of patients suggest that the deterioration of health is extremely rare. Nevertheless, the likelihood of adverse reactions should not be discounted.

In some cases, vaginal suppositories cause irritation of the vaginal mucosa, which is accompanied by itching and burning. These sensations can occur both after the first injection and on the second or third day of therapy. Symptoms disappear on their own immediately after the end of therapy, although severe itching and soreness are indications for discontinuation of the drug.

Much less common side effects from the digestive system. Some patients complain of nausea, vomiting, loss of appetite, as well as constipation and diarrhea. Sometimes there is a metallic taste or increased dryness in the mouth.

What other complications can cause candles "Neo-Penotran"? The instructions indicate that patients occasionally show symptoms of the nervous system - headaches and dizziness. If the medication is used too long, seizures, peripheral nephropathy and some psycho-emotional disorders may appear.

People with hypersensitivity to the components of the drug show an allergic reaction, which is accompanied by the appearance of a rash, urticaria, itching, swelling and burning.

Overdose and its signs

Today, many doctors prescribe patients to candles "Neo-Penotran Forte." The price of the drug is quite affordable, and the effect of its use appears quickly. Nevertheless, it is necessary to take this medicine with caution - be sure to follow all the doctor's instructions.

Cases of overdose are rarely registered, but it is possible. If too much metronidazole gets into the blood, it may cause abdominal pain, nausea and vomiting. Also, some patients complain of an unpleasant metallic taste in the mouth. An overdose of the drug can cause dizziness, convulsions, ataxia, paresthesia. In some cases, there is a staining of urine in a dark color. About the same symptoms occur when using too large doses of miconazole.

In the presence of such violations should consult a doctor. As a rule, specific treatment is not carried out - you only need to stop taking the drug for a while. If necessary, symptomatic therapy is needed.

Interaction with other drugs

Quite often in modern gynecology is used in the treatment of candles "Neo-Penotran 7". The price of the drug is quite acceptable, and its effectiveness is confirmed by practice. But if you are prescribed this medicine, be sure to tell the doctor about other means you are taking.

The active ingredients of this drug interact with anticoagulants, enhancing their effect. In addition, this medicine affects the level of theophylline and procainamide in the blood. "Neo-Penotral" can also inhibit the activity of some drugs taken in case of disturbances in the cardiovascular system, so patients sometimes have an arrhythmia. The active substances of suppositories interact with lithium preparations, enhancing their damaging effects.

On the other hand, cimetidine increases the level of metronidazole in the blood. At the same time, the simultaneous administration of this drug with phenobarbital leads to a decrease in the amount of metronidazole.

special instructions

Of course, many patients are interested in questions about what constitutes the drug "Neo-Penotran" (candles) - instructions, price, indications and contraindications. But there is some additional information that you should definitely read before starting treatment.

At the time of therapy is to abandon sexual intercourse. After all, the risk of infecting a partner during an act is very high. In addition, candles "Neo-Penotran Forte" damage to rubber and latex, which makes the use of such means of protection and contraception ineffective.

It is also categorically contraindicated to consume alcohol during therapy. Otherwise, there is a high probability of the appearance of certain mental changes.

This medicine is not used to treat girls who have not had sex. According to research, the drug does not affect the reaction rate, the ability of a person to drive a car, etc.

The drug "Neo-Penotran" (candles): price and analogues

Naturally, many patients are primarily interested in the cost of a particular drug. So how much will the drug Neo-Penotran (candles) cost? Price, of course, can fluctuate. On average, 14 suppositories will cost 700-800 rubles. "Neo-Penotran Forte" is a bit more expensive - 900-1000 rubles. Naturally, the cost depends on the manufacturer’s company, the form of the medicine and the financial policy of the pharmacy.

What to do if you do not fit candles "Neo-Penotran"? Analogs are cheaper, of course, exist. For example, such means as Labilact, Mikozhinaks, as well as Dalatsin, Lecran, and Ketoconazole are considered quite effective. In some cases, doctors prescribe "Metrogil", "Vagilak" and some other medicines.

The drug "Neo-Penotran" (candles): reviews of doctors and patients

Many women today face the problem of inflammatory and infectious diseases of the sexual sphere. And quite often “Neo-Penotran” helps to get rid of this or that disease.

Reviews of experts confirm the effectiveness of this drug. Yes, and patients note the rapid disappearance of the main symptoms of the disease. The disadvantages of this tool can be attributed perhaps that its relatively high cost. Some patients also complain of burning sensation when administering suppositories. However, it is necessary to suffer, because it is not too high a price, which will have to be paid for a quick and complete recovery.

What is Neo-Penotran

Vaginal suppositories contain an active substance such as metronidazole. It has antimicrobial properties. Miconazole nitrate is also present. The basis in the production of the drug is taken witepsol.

Depending on the concentration of the active components, candles are divided into several varieties:

  • Neo-Penotran containing 500 mg of metronidazole and 100 mg of miconazole nitrate.
  • Neo-Penotran Forte - metronidazole contains 750 mg in dosage, and miconazole nitrate - 200 mg.
  • Neo-Penotran Forte - L - contains the same dosages of active substances as the variant with the label "Forte". But still included in the composition of lidocaine - 100 mg.

Metronidazole is a synthetic medicine with trichomonacid, antimicrobial, anti-ulcer and antibacterial effect. Affects gardnerella, Trichomonas, Helicobacter pylori, esherichia and amoebas. Vaginal suppositories with metronidazole effectively treat vaginitis, urethritis, colpitis, endocervicitis, nonspecific bacterial vaginosis.

Miconazole nitrate has anti-inflammatory and fungicidal properties. Candida strains, the fungus Aspergillosis and Malassezia, Staphylococcus and Streptococcus are oppressed without changing the intrinsic composition of the vaginal microflora and the acid-base environment.

Witepsol is a compound of unsaturated fatty acids, compatible with a variety of medicinal substances. Lidocaine gives an analgesic effect, reduces irritation, itching and burning.

Miconazole destroys the cells of the fungus, and metronidazole prevents the growth of microbes in the blood. This ability allows you to use the drug in the treatment of thrush, because it affects the focus of the accumulation of fungal infections.

Indications for use suppository

The manufacturer recommends the use of candles Neo-Penotran Forte for such indications as:

Often, when a burning sensation occurs and abnormal vaginal discharge appears, women try to self-medicate and buy tablets or candles from the fungus, thinking that they are worried about thrush. This can not be done, because each drug, including Neo-Penotran Forte, has its own contraindications.

Who should not use candles Neo-Penotran:

  • To virgins.
  • Girls under 14 years old.
  • People sensitive to the components of the drug.
  • Nursing and pregnant women in 1 trimester.
  • Patients with diseases of the central nervous system, porphyria, liver disorders, epilepsy.

During the period of use of suppositories, it is strictly forbidden to consume alcohol.

How to treat vaginal infections with candles Neo-Penotran Forte

If the doctor did not tell anything about the features of treatment with suppository Neo Penotran, the patient will find this information in the instructions for use of the intravaginal drug. The classical scheme involves the introduction of a suppository for the night for 1 week. In acute infectious states of the genital tract, the course of therapy can reach 2 weeks.

The suppository is inserted deep into the vagina with a finger clad in a disposable fingertip. The use of the medicine at bedtime, when the body is in a supine position all night, allows the active substances to completely dissolve and penetrate into the vaginal mucosa.

How much time can and should be used Neo-Penotran candles? The instructions say that the therapeutic course is for 7 days. But in severe cases, when a woman has recurrent inflammation or a resistant infection, the gynecologist is entitled to increase the daily dosage of Neo-Penotran Forte to two candles and extend the course for another 7 days.

Application during menstruation

Adult women can ask the doctor such a question whether it is possible to be treated with candles Neo-Penotran during menstruation. Some gynecologists recommend to refrain from invading the sexual system until the end of bleeding, but in fact it is allowed to use intravaginal drug during the menstrual period.

It happens that menstruation begins in the course of treatment. In this case, the course can not be interrupted. But in order for therapy not to be useless, a woman should do without hygienic tampons and use only pads.

Side effects

In most cases, the body perceives the active components of Neo-Penotran well, but side effects sometimes occur that cause anxiety to patients. These are headaches and dizziness, convulsions and psycho-emotional changes. Constipation and diarrhea, nausea and vomiting may occur on the part of the digestive system. There is a metallic taste in the mouth or dryness appears, appetite disappears.

Кожа гиперчувствительных особ может отреагировать на медикамент высыпаниями, отёками, жжением, крапивницей. Внутри влагалища из-за раздражения слизистой могут усиливаться зуд и жжение. Неприятные ощущения возникают либо сразу после первой свечи, либо на 2 – 3 день лечения. Symptoms should disappear on their own as the course ends, although pain and increasing itching are already a reason to cancel the medication.

What to replace Neo Penotran Forte in case of individual intolerance of the composition and in the presence of contraindications:

  • Clomesol
  • Ketonazole.
  • Klion-D 100.
  • Trichopol.
  • Klevazol.
  • Gravagin.
  • Mikogal
  • Livarol.
  • Ginalgin.
  • Pulsitex.
  • Metromikon-Neo and others.

Neo-Penotran has no exact analogues, the above preparations have similar pharmacological properties, but differ in composition.

Price and reviews

You can buy the drug at the pharmacy, and at an affordable price, you can order medicine from the online store. 14 suppositories labeled "Forte" are sold for 900 - 1000 rubles. Regular Neo-Penotran costs 700 - 800 rubles. The difference depends on the manufacturer and pricing of a particular pharmacy.

Reviews of doctors and patients testify to the high efficiency of candles Neo-Penotran Forte.

Symptoms of thrush, vaginitis, fungal vulvovaginitis disappear quite quickly and after the course is over, the doctors fix a full recovery. Some consumers complain of burning after administration of the suppository. If the discomfort does not increase, it is worth enduring and finishing the course.

Types of candles, composition and effectiveness

There are three types of drugs: vaginal tablets and candles "Neo-Penotran", "Neo-Penotran Forte" and "Neo-Penotran Forte L". All of them contain as active components metronidazole and miconazole, the difference in doses of these substances and subsequent schemes of using suppositories. The preparation "Neo-Penotran Forte L" additionally contains lidocaine - a local anesthetic.

Packing the usual "Neo-Penotran" (14 pieces) costs from 774 rubles. Option "Forte" - from 934 rubles for seven pieces. The price for the same package "Forte L" - from 979 rubles. (Data for December 2017). Differences drugs are presented in the table.

Table - Varieties of candles from the series

Each component of the drug acts not only at the level of the vaginal mucosa, but also enters the systemic circulation. Due to this, stable concentrations of active substances are created throughout the treatment. The action of "Neo-Penotran" is expressed in the following.

  • Metronidazole. It interacts with pathogens, integrates into their genetic material and leads to death. Metronidazole is active against trichomonads, gardnerella, peptokokkam, peptostreptokokkam.
  • Miconazole. Suppresses the synthesis of ergosterol - a component of the cell wall of fungi, thereby providing a powerful fungicidal effect. This is an excellent tool for the treatment and prevention of thrush. In addition, miconazole has a detrimental effect on staphylococci and streptococci.

When prescribed

The use of "Neo-Penotran" effectively in the following situations:

  • for the treatment of exacerbation - an episode of thrush and prevention of candidal vaginitis, with chronic cervicitis,
  • with inflammation - associated with trichomonas infection,
  • in violation of the flora - the vagina and with gardnerelleze,
  • to heal the cervix - for example, after treatment with radio waves or current,
  • on the eve of childbirth - and vaginal surgery,
  • in the treatment of dysplasia - moderate and mild, cervical erosion.

The drug can be used in complex treatment of genital infections, such as chlamydia, ureaplasmosis, mycoplasmosis. However, it does not act on the causative agents of these diseases. Chlamydia, ureaplasma and mycoplasma must be sanitized by taking oral antibiotics.

Restrictions on use

Part of the drug metronidazole and miconazole enter the systemic circulation, are metabolized in the liver. Contraindications for using the remedy are the following states:

  • hypersensitivity reactions - to metronidazole, miconazole or formative components,
  • liver disease - especially with a combination of several drugs
  • blood diseases - and bone marrow,
  • convulsions, epilepsy - in the anamnesis.

"Neo-Penotran": instructions for use

The scheme of use of drugs must be determined by the doctor individually. Standard appointments include the following:

  • on the suppository in the morning and evening - for ten days,
  • on suppository in the evening - for 14 days,
  • on the suppository twice a day - for 14 days.

For the treatment of Trichomonas colpitis, preference should be given to suppositories with a higher dosage of metronidazole (Neo-Penotran Forte and Neo-Penotran Forte L), as well as supplemented therapy with oral anti-trihomonas preparations. Reviews of "Neo-Penotran" in the treatment of this infection confirm that a little money. The risk of chronic process increases, complications develop (for example, cystitis, urethritis).


When using vaginal tablets, you must first moisten them in water. The medicine should be laid in a half-bent position or lying down. In the box with the "Neo-Penotran" there are special tips on the finger to more comfortable to introduce the drug.

Candles "Neo-Penotran" should not be used for menstruation - it is better to suspend the course of treatment, and continue after the end of the bleeding.

It is necessary to provide an option with an increase in discharge during the course. In the presence of bloody or light discharge from the "Neo-Penotran" use additional personal hygiene products.

Side effects

According to the reviews of doctors, the treatment with "Neo-Penotran" is usually well tolerated when the doses and regimens are observed. But the following side effects of the drug may be noted:

  • local manifestations - itching, burning, swelling, redness at the injection site,
  • on the part of the gastrointestinal tract - a metallic taste in the mouth, bloating, diarrhea or a slowdown in the evacuation of feces, nausea, heartburn, abdominal pain,
  • others - headache, migraine and even convulsive muscle contractions with prolonged uncontrolled intake, increased fatigue.

In case of overdose, the feeling of nausea is aggravated, vomiting, dizziness, convulsions appear. If you are taking a vaginal tablet or a candle inside, you should flush the stomach or induce vomiting. If bloody secretions from "Neo-Penotran" appear, you should watch them, and in case of an increase, seek medical help.

Candles Neo-Penotran

With genital infections, a particularly effective form of release is vaginal suppositories that act directly on the pathology center. The drug Neo-Penotran, produced in the form of candles, has proven itself well. The drug is used in gynecology, has pronounced antibacterial, antifungal, antiprotozoal properties. Vaginal suppositories are not prohibited during pregnancy and lactation, but require medical attention.

Neo-Penotran - composition

The chemical formula of vaginal suppositories harmoniously combines two components - metronidazole and miconazole nitrate. The first synthetic substance violates the integrity of the membranes of bacteria and protozoa, promotes mass death and imperceptible elimination from the body. The second component of Neo-Penotrana exhibits increased activity against fungi, acts on the same principle.

It turns out that Neo-Penotran is a combined treating agent capable of overcoming any infection of the genital sphere, is widely used in modern gynecology. The chemical composition of Neo-Penotran supplements a substance called Witepsol, as an auxiliary element to enhance the therapeutic effect, accelerate the natural healing process.

Neo-Penotran - application

The effect of vaginal suppositories is instantaneous, but only for medical reasons. It is important not only to remove the signs of the disease, but also to detect their cause in a timely manner. Only in this case, the prescribed dosage in the shortest possible time allows the patient to feel the long-awaited relief. So, the topical application of Neo-Penotran is appropriate in the following clinical pictures:

  • anaerobic vaginosis,
  • vaginal candidiasis,
  • bacterial vaginosis
  • non-specific vaginitis,
  • congestive vaginitis,
  • mixed vaginal infections
  • Trichomonas vulvovaginitis.

When the sensation of burning and the appearance of specific discharge from the vagina of the patient transgress to self-treatment. Doing this is contraindicated, especially vaginal plugs Neo-Penotran have their own contraindications. Before prescribing the specified medication, the doctor conducts a detailed diagnosis. So, consultation with a specialist before intravaginal administration of the drug Neo-Penotran is mandatory. Contraindications to the use of these vaginal suppositories are as follows:

  • the body's sensitivity to synthetic components of candles,
  • extensive lesions of the central nervous system,
  • first trimester pregnancy
  • porphyrias,
  • liver dysfunction
  • epilepsy,
  • age limit up to 14 years
  • lactation period
  • disorders of hematopoiesis,
  • in combination with alcohol,
  • virginity.

Neo-Penotran - instruction

If the effect of side effects Neo-Penotran does not stop, it is recommended to cancel the use of vaginal suppositories, choose an analogue. However, in most cases, such anomalies are temporary, disappear after 2-3 days without additional cancellation of the treating agent. Instructions Neo-Penotrana tells how to use candles, in what doses, for how long, but is not a guide to use. Any adjustments and appointments made by the doctor. It is necessary to introduce 1 suppository of Neo-Penotran 1 at night and in the morning for 7 days. In the acute stage, the treatment course reaches 2 weeks.

Neo-Penotran forte during pregnancy

When carrying the fetus candles use only as directed by the gynecologist. In the first trimester of pregnancy, the drug Neo-Penotran is contraindicated, in the second and third - it is permitted in the absence of a threat to intrauterine development. Doses are determined individually, administered vaginally. Neo-Penotran forte during pregnancy successfully removes the symptoms of thrush, reduces the activity of other sexually transmitted infections.

If such vaginal suppositories are prescribed by the doctor during lactation, breastfeeding should be replaced with artificial. This is a prerequisite for the safety of the health of the newborn. The restriction is temporary, and it is allowed to return the child to HB only 24-48 hours after the cessation of intensive therapy with this antibacterial agent.

Neo-Penotran during menstruation

Opinions of experts on a given topic are very controversial. Neo-Penotran vaginal suppositories for menstruation are not prohibited to use, however, doctors still recommend their patients to wait for the vaginal discharge to stop and start a course. If menstruation appeared during the passage of intensive therapy, the use of these candles do not stop. About Neo-Penotrana and monthly it is better to talk with a specialist.

Pharmacodynamics and pharmacokinetics

The drug contains a number of components that have different effects on vaginal microflora. Detect in the blood plasma all components of the drug can be within 3 days.

Miconazole - antifungal agent. Depresses the livelihoods of major pathogenic fungialso exhibits activity to some gram-positive bacteria. Practically not absorbed into the bloodstream through the mucous membrane.

Metronidazole destructive for anaerobic bacteria and some the simplest. Affects Trichomonas vaginalisand Gardnerella vaginalis. 20% of the administered dose enters the blood. Excreted from the body through the kidneys.

Part Neo-Penotrana Forte L additionally included lidocainehaving analgesic effect. Already after 4-6 minutes after administration, the substance begins to act. The substance inhibits the process of conducting nerve impulses through neuronal membrane. It is then metabolized in the liver and slightly excreted through the kidneys.


  • drug allergy on the substances that make up the funds
  • severe forms of liver and kidney disease,
  • epilepsy and other serious diseases of the central and peripheral nervous system,
  • pregnancy (1 trimester)
  • Also, the drug is contraindicated in children under 14 years.

Instructions for use (method and dosage)

Instructions on Neo-Penotran

Vaginal candles are inserted deep into the vagina, overnight. 1 piece for 7 days. In severe cases of the disease, treatment can be extended to 14 days.

Instructions Neo-Penotran Forte and Neo-Penotran Forte L

Most often, the drug is prescribed on the 1st suppository for the night. Course 7-14 days. In the package, a single fingertip is attached to the medicinal product. They should be used when administering medication to the vagina.

Analogs of Neo-Penotran

The closest analogues of vaginal suppositories: Metromixon-Neo (candles too) and Klion-D 100.

Also, analogues of the drug are: Ginalgin, Klomezol, Klevazol, Pulsitex, Gynofort, Candibene, Candisan, Gravagin, Ketonazole, Livarol, Clotrimazole, Metrogil Vaginal, Mikogal, Metronidazole, Econazole, Trichopol.

Price unparalleled Neo-Penotran Forte may differ significantly from the original.

Reviews on Neo-Penotran

Reviews for candles Neo-Penotran Forte and Forte L are generally good. The drug helps many in the fight against thrush, especially in the chronic form. Itching and burning often occur as a side effect, but the symptoms quickly subside.

Reviews during pregnancy: Women are satisfied with the result of using candles during pregnancy. Most often, the drug does not harm the fetus and effectively fights unwanted diseases.


Education: She graduated from the Rivne State Base Medical College with a degree in Pharmacy. She graduated from Vinnitsa State Medical University. M.I.Pirogov and internship at its base.

Experience: From 2003 to 2013, she worked as a pharmacist and head of a pharmacy kiosk. She was awarded diplomas and insignia for many years of diligent work. Articles on medical topics were published in local editions (newspapers) and on various Internet portals.

Neo-penotran preparations are very old and instead of effective treatment of vaginitis, they often bring only a lot of side effects: allergic reactions are especially with lidocaine, burning is very strong, the skin slashes in this place, forget about sex mono and others. I think this is also related to the production located in Turkey, where the control of production is minimal and its cost in Turkey is only $ 5. It is sold only in Russia, Kazakhstan, Ukraine and Turkey. If you want these components, then it is better to buy Metromicon neo save twice the cost, and the raw materials in the metromicone are Turkish from the factory itself.

Letter No. 04I-28/11 of the Federal Service for Roszdravnadzor of the Russian Federation of January 25, 2011 On withdrawal of the medicinal product from circulation The FEDERAL SERVICE FOR SUPERVISION IN THE SPHERE OF HEALTH CARE AND SOCIAL DEVELOPMENT The Public Health and Social Development Supervision Service informs that ZAO Bayer carried out a recall from the circulation of the drug Neo-Penotran Forte, vaginal suppositories (blisters) No. 7 / complete with fingertips / series 10018 manufactured by Ambil Pharmaceutical Co. Ltd., Turkey, due to its incompatibility with the requirements of regulatory documentation on the indicator "Description". The implementation of the batch of this drug of the specified series was previously suspended by the letter of Roszdravnadzor of 04.10.2010 No. 04I-964/10. Roszdravnadzor invites Bayer CJSC to provide information on withdrawal from circulation and destruction of the specified series of the medicinal product in the prescribed manner. The Federal Service for Supervision in the Sphere of Health and Social Development offers the subjects of the circulation of medicinal products to check the availability of the specified batch of medicinal product and submit to the territorial body of Roszdravnadzor information about its withdrawal from circulation. Territorial bodies of Roszdravnadzor to hold events in accordance with the Procedure provided by the letter of Roszdravnadzor dated February 8, 2006 No. 01I-92/06 "On the organization of work of the territorial departments of Roszdravnadzor with information on substandard and falsified drugs". Acting Head E.A.Telnova Who is this TURKISH city still buying. Its price is several times higher than that of Europeans, and its efficiency and safety are lower.

The first time I did not understand that it was because of Neo-Penotran. All the skin from the genital lips just peeled off like a burn, everything ached and burned, slept, washed, and it was like hell to go to the toilet, not to mention sex. I restored the mucous 2 weeks. I forgot about this situation. Then again the doctor appointed these candles and on the 2nd day the same thing began! Some kind of horror! Why it is impossible to ask about allergies to the components, but to prescribe such expensive medicines?! ((((Especially since I have honey on my card that is allergic to metronidozole

Release form and drug composition

The drug Neo-Penotran is available in the form of suppositories for vaginal use (candles) in blisters of 7 pieces, 1 or 2 blisters in a carton box with the attached detailed description. In the box are embedded applicators with fingertips for ease of inserting suppositories into the vagina.

The composition of each candle contains the most important active ingredients - Metronidazole 500 mg and Miconazole nitrate 100 mg, in addition to the composition of the drug includes excipients.

Pharmacological properties

Neo-Penotran is a complex drug used locally in gynecology for the treatment and prevention of bacterial, parasitic and fungal infections.

The nitrate contained in the suppositories of Miconazole has a pronounced therapeutic effect on Candida fungi and some other types of fungi.

The drug is highly effective against many pathogens of gram-positive and gram-negative microflora, including trichomonads, cardrenella.

Method of application and dosing regimen

The preparation Neo-Penotran is intended only for vaginal use. Patients older than 18 years old are prescribed 1 suppository 1 time per day deep in the vagina before going to bed at night. The duration of the course of therapy is 1 week, if necessary, the doctor may extend the treatment up to 10 days.

For ease of administration of the drug in the vagina, a woman is recommended to lie on her back, spread her legs wide apart, and use the included fingertip. After that you should wash your hands thoroughly with soap and water.

Use during pregnancy and lactation

Neo-Penotran is not prescribed for the treatment of women in the first trimester of pregnancy, due to the lack of data on the safety of the influence of active substances on the development of the fetus. In the second and third trimesters of pregnancy, drug treatment is possible only if indicated in the case when the benefits for the future mother outweigh the possible risks for the future child.

If it is necessary to use suppositories during breastfeeding, a woman is recommended to interrupt the feeding process.

Drug overdose

Since the local application of the drug absorption of active active substances in the general bloodstream is low, the risk of overdose is practically absent. In case of accidental ingestion of suppositories (for example, in small children), it is recommended to flush the stomach and give it to absorb activated charcoal.

The interaction of the drug with other drugs

Suppositories Neo-Penotran is not recommended to be simultaneously administered with Metronidazole tablets for oral use, as in this case the risk of systemic side effects increases.

Not recommended the simultaneous use of suppositories of the drug with vaginal tablets or cream, which includes Metronidazole, as in this case, the risk of side effects increases significantly.

Release form and composition

Dosage form of Neo-Penotran Forte - vaginal suppositories, which are a flat body with a rounded end, almost white or white (7 pieces in a plastic blister, 1 blister in a cardboard box).

Active substances in the composition of 1 suppository:

  • Neo-Penotran: metronidazole in the amount of 1/2 g + miconazole nitrate in the amount of 1/10 g + excipients (witepsol of 1.9 grams).
  • Neo-Penotran Forte: metronidazole in the amount of 3/4 g + miconazole nitrate in the amount of 1/5 g + excipients (1.5 grams of Witepsol).
  • Neo-Penotran Forte L: metronidazole in the amount of 3/4 g + micronazole nitrate in the amount of 1/5 g + lidocaine - excipients (witepsol, 1.44 grams).

Pharmacological effect

The active ingredients (miconazole and metronidazole) of the drug have a local antibacterial, antifungal and antiprotozoal effects.

Thanks to this combination of components, Neo-Penotran suppositories are effective in the treatment of diseases caused by the following pathogens: Gardnerella vaginalis. Trihomonas vaginalis. Pathogenic fungi (Candida albicans also). Anaerobic bacteria (including anaerobic streptococcus). Neo-Penotran is also effective against gram-positive bacteria.

Dosage and method of use

The instructions for use indicate that vaginal suppositories Neo-Penotran Forte should be inserted deep into the vagina using disposable fingertips contained in the package.

  • Enter intravaginally 1 suppository for the night for 7 days.
  • When recurrent vaginitis or vaginitis resistant to other types of treatment, Neo-Penotran Forte should be used within 14 days.

For elderly patients older than 65 years, no dosage regimen adjustment is required.

Drug interactions

When using the drug, you must consider the interaction with other drugs:

  1. The interaction of metronidazole with ethanol can cause disulfiram-like reactions.
  2. With simultaneous use with lithium, an increase in lithium toxicity may be observed.
  3. With simultaneous use with phenobarbital there is a decrease in the concentration of metronidazole in the blood.
  4. With simultaneous use with oral anticoagulants, there is an increase in anticoagulant action.
  5. With simultaneous use with disulfiram possible side effects from the central nervous system (psychotic reactions).
  6. With simultaneous use with cimetidine, the concentration of metronidazole in the blood may increase and the risk of neurological side effects may increase.
  7. With simultaneous use of phenytoin, there is a decrease in the concentration of metronidazole in the blood while increasing the concentration of phenytoin.
  8. With simultaneous use with astemizole and terfenadine, metronidazole and miconazole inhibit the metabolism of these substances and increase their plasma concentrations.

We picked up some reviews of people using the drug Neo-Penotran Forte:

  1. Irina . I occasionally have bacterial vaginitis - from malnutrition, colds and weakened immunity. I have already learned to fight with him - every six months I go through therapy with candles Neo-Penotran Forte, which I once wrote to me as a gynecologist. I like the fact that they effectively reduce the amount of discharge, eliminate itching.
  2. Kseniya . Hello, I want to share the experience of using this drug, I tried to get pregnant for two years and didn’t work, in the end our local gynecologist put on bacterial vaginosis and prescribed a whole bunch of drugs for 1000 rubles, I did not listen and went for a consultation to a paid clinic, they said that I need to collect all the tests, it is also expensive, and I mentioned this drug, I decided to buy the risk at my own risk ... and what do you think, two weeks after the end of the reception is pregnancy, so it helps, in the first days of taking strength and n Astroenia, and then how was born again, I advise. girls!
  3. Marina Last month, for the first time, I came across manifestations of thrush, which I had previously only read in Internet reviews. Allocation began to look like "cottage cheese", itching, burning. The doctor wrote me candles for Neo-Penotran Forte, told me to use it for seven days, and then get tested. The drug helped to cope with discomfort, it was easily tolerated.

How to replace Neo Penotran Forte in case of individual intolerance of the composition and in the presence of contraindications:

  • Clomesol
  • Ketonazole.
  • Klion-D 100.
  • Trichopol.
  • Klevazol.
  • Gravagin.
  • Mikogal
  • Livarol.
  • Ginalgin.
  • Pulsitex.
  • Metromikon-Neo and others.

Neo-Penotran has no exact analogues, the above preparations have similar pharmacological properties, but differ in composition.

Before using analogues consult your doctor.

Analogues of the drug Neo-Penotran Forte

Analogue cheaper from 140 rubles.

Manufacturer: Embil Pharmaceutical Co. Ltd. (Turkey)
Forms of release:

  • Suppose vaginal, 14 pcs., Price from 739 rubles
Prices for Neo-Penotran in online pharmacies
Instructions for use

Neo-Penotran is an antimicrobial drug for the local treatment of gynecological diseases of Turkish origin. The suppositories contain 2 active ingredients: metronidazole and miconazole nitrate. It is prescribed for bacterial vaginosis, trichomonas vaginitis.

Analogue cheaper from 408 rubles.

Manufacturer: Nizhpharm (Russia)
Forms of release:

  • Candles 400 mg. 5 pcs., Price from 471 rubles
  • Candles 400 mg. 10 pcs., Price from 665 rubles
Prices for Livarol in online pharmacies
Instructions for use

Livarol - vaginal suppositories manufactured by the Russian company Nizhfarm. Intended for the treatment of acute and chronic mycosis of the vagina. Available in cartons of 5 pieces, each of the candles contains 400 mg. ketoconazole.

Analogue cheaper from 798 rubles.

Manufacturer: Polfa (Poland)
Forms of release:

  • Tablets 250 mg, 20 pcs., Price from 81 rubles
  • Candles 400 mg. 10 pcs., Price from 665 rubles
Prices for Trichopolum in online pharmacies
Instructions for use

Trichopolum is a Polish antibacterial drug for systemic use, which is prescribed for the treatment of trichomoniasis, amebiasis, periodontal infection and other diseases caused by microorganisms that are susceptible to metronidazole.

Analogue cheaper from 515 rubles.

Manufacturer: Firn M (Russia)
Forms of release:

  • Candles 10 pcs. in the package, price from 364 rubles
  • Candles 400 mg. 10 pcs., Price from 665 rubles
Prices for Vagiferon in online pharmacies
Instructions for use

Glenmark (India) Candide - clotrimazole-based vaginal tablets at a dosage of 500 mg. May be prescribed for the treatment of vaginal infections caused by the activity of yeast-like fungi, as well as trichomoniasis. By contraindication contains differences with Zalain. Before starting treatment, be sure to consult with a specialist.

Manufacturer: Gedeon Richter (Hungary)
Forms of release:

  • Tab. wag 10 pcs., Price from 0 rubles
  • Candles 400 mg. 10 pcs., Price from 665 rubles
Prices for Klion-D 100 in online pharmacies
Instructions for use

Klion-D 100 is slightly different in the form of release and is sold in the form of vaginal tablets, which contain the same active ingredients as in Neo-Penotran, but in the same dosage. Indications and contraindications are not significantly different.

Analogue cheaper from 567 rubles.

Manufacturer: Pharmaprim (Moldova)
Forms of release:

  • Suppose vaginal 500 mg + 100 mg, 14 pcs., Price from 312 rubles
  • Candles 400 mg. 10 pcs., Price from 665 rubles
Prices for Metromikon-Neo in online pharmacies
Instructions for use

Gedeon Richter (Hungary) Klion-D 100 is slightly different in form of release and is sold in the form of vaginal tablets, which contain the same active ingredients as in Neo-Penotran, but in the same dosage. Indications and contraindications are not significantly different.